2024 Thbs4 reporter mouse

Thbs4 reporter mouse

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Web7 Aug 2024 · Cells were collected from adult mouse heart, skeletal muscle, colon, and urinary bladder based on their expression of reporters and/or antibody-recognized epitopes for platelet-derived growth... We would like to show you a description here but the site won’t allow us. We would like to show you a description here but the site won’t allow us. WebGold-standard specificity, sensitivity, and reproducibility Designed to detect virtually any transcript Best-coverage assays available to detect the highest number of transcript variants possible Performance guaranteed Already know your target of interest? Search for a pre-designed TaqMan Gene Expression Assay using the tool below. Gene Expression

Thbs1 induces lethal cardiac atrophy through PERK-ATF4 ... - Nature

http://www.informatics.jax.org/assay/MGI:3639251 Web1 May 2024 · The inhibition of THBS4 may provide therapeutic benefits that can prevent the formation of abdominal adhesions. ... Studying the roles of mouse Sox10 by conditional gene targeting. biofucal

21828 - Gene ResultThbs4 thrombospondin 4 [ (house mouse)]

WebView In situ reporter (knock in) gene expression results for Thbs4 with structure, expression level, image, reference. Web1 Jul 2014 · The mouse strain B6.129P2-Thbs4 tm1Dgen/J (Thbs4 KO in C57BL/6 background) was obtained from The Jackson Laboratory (Bar Harbor, Maine, USA). In this strain, the Thbs4 gene was inactivated by replacing 14 nucleotides in the first intron with a … WebAnti-THBS4 Antibody Products. Anti-THBS4 antibodies are offered by a number of suppliers. This target gene encodes the protein 'thrombospondin 4' in humans and may also be known as TSP4 and TSP-4. Structurally, the protein is reported to be 105.9 kilodaltons in mass. Based on gene name, canine, porcine, monkey, mouse and rat orthologs may also ... daikin service checker 4 for sale

(PDF) Sa1137 AN ADHESIOGENIC ROLE OF THBS4 IN THE

Anti-THBS4 Antibody Products Biocompare

Web26 Sep 2016 · Here we show that Thrombospondin-4 (Thbs4) regulates skeletal muscle integrity and its susceptibility to muscular dystrophy through organization of membrane attachment complexes. Loss of the Thbs4 gene causes spontaneous dystrophic changes … Web24 Jun 2024 · Mechanistically, Thbs1 binds and activates the endoplasmic reticulum stress effector PERK, inducing its downstream transcription factor ATF4 and causing lethal autophagy-mediated cardiac atrophy.... daikin service checker 4 toolWeb16 Sep 2010 · Thrombospondin-4 (THBS4) is a member of the extracellular calcium-binding protein family and is involved in cell adhesion and migration. The aim of this study was to evaluate the potential role of deregulation of THBS4 expression in colorectal carcinogenesis. Of particular interest was the possible silencing of expression by methylation of the CpG … daikin service checker 4 manual

"Web8 May 2024 · Using Thbs4−/− mice and TSP-4 shRNA, we found that TSP-4 mediated pro-angiogenic functions in cultured EC and angiogenesis in vivo in response to TGF-β1. We observed~3-fold increases in tumor... " - Thbs4 reporter mouse

Thbs4 reporter mouse

Thrombospondin expression in myofibers stabilizes muscle …

Web26 Sep 2024 · Loss of the Thbs4 gene causes spontaneous dystrophic changes with aging and accelerates disease in 2 mouse models of muscular dystrophy, while overexpression of mouse Thbs4 is protective and mitigates dystrophic disease. TSP-4 plays a role in … http://www.informatics.jax.org/assay/MGI:3639251

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WebThbs4 - thrombospondin 4 (house mouse) Predicted to enable several functions, including fibronectin binding activity; heparin binding activity; and laminin-1 binding activity. Involved in behavioral response to pain; regulation of tissue remodeling; and response to endoplasmic reticulum stress. Located in collagen-containing extracellular ... Web2 Dec 2015 · 1. Mouse models. Thbs4-deficient mice on a C57Bl/6 genetic background were purchased from the Jackson Laboratories (#005845).Their genotyping was performed with the primers 5´-GGG TGG GAT TAG ATA AAT GCC TGC TCT-3´, 5´-GGA GAG AGA ATA GCA AGA TCA GCT C-3´, and 5´-AAC AAG CAA TGG AAG GCA GAC CCT G-3´, giving rise to a …

Web8 Jan 2024 · In skeletal muscle, overexpression of Thbs4 dramatically enhanced sarcolemmal stability that rescued mouse models of muscular dystrophy through a mechanism involving enhanced integrin and... Web27 Aug 2013 · This robust postinjury astrogenic response required SVZ Notch (190198) activation modulated by Thbs4 via direct Notch1 receptor binding and endocytosis to activate downstream signals, including increased Nfia (600727) transcription factor expression important for glia production.

WebView In situ reporter (knock in) gene expression results for Thbs4 with structure, expression level, image, reference.

WebWe focused our attention on Thrombospondin 4 (Thbs4), one of the 5 members of the Thrombospondin family of large, multidomain, extracellular matrix proteins. In post-natal and adult brain Thbs4 mRNA and protein are specifically expressed in the neurogenic regions, …

WebRecombinant Human Thrombospondin‑4 (rhThrombospondin-4) is coated to 96 well plates at 10 µg/mL (100 µL/well) overnight then reduced with 20 mM DTT for 30 minutes. When 2 x 10 4 cells/well are added to rhThrombospondin‑4 coated plates, ≥50% will adhere after one hour at 37 °C. Optimal dilutions should be determined by each laboratory ... biofuel definition geographyWeb2 days ago · If you're a Resident Evil 4 fan or are at all following the game online, you might have noticed some goofy art over the last month involving the character Ashley looking strangely rodent-like ... daikin service checker 4 software downloadWeb22 Jun 2024 · THBS4 is overexpressed both in HCC tissues and cell lines. The overexpression of THBS4 in HCC patients’ samples in contrast to normal samples was first discovered by analysis of StarBase v3.0 (Figure 1A, P = 4.0e-36), which result was identical with the result from analysis of GEPIA (Figure 1B, *P < .01). Furthermore, the expression … bio fuel ethanol fire indoorWeb8 Jan 2024 · Human and mouse Thbs4 contain a RGD domain in the third type-3 repeat 60, ... The Thbs3 β-galactosidase reporter mouse strain was created from ES cell clone 19211A-A12, generated by Regeneron Pharmaceuticals, Inc. and obtained from the KOMP … biofuel from water hyacinthWebDescription: LS-F7671 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the Quantitative detection of Mouse THBS4 / Thrombospondin 4 in samples of Cell Culture Supernatants, Cell Lysates, Plasma and Tissue Homogenates. It is based upon a … daikin service checker 4Web7 Nov 2024 · To determine if changes in THBS1 and THBS4 mRNA were accompanied by similar changes in thrombospondin proteins, granulosa cell lysates were subjected to western blotting. THBS1 protein was detected as a single band of 160 MW ().Granulosa cell THBS1 was low 0–24 h after hCG, then rose to higher levels at 36 h hCG ().THBS4 was … daikin service checker priceWebComplete information for THBS4-AS1 gene (RNA Gene), THBS4 Antisense RNA 1, including: function, proteins, disorders, pathways, orthologs, and expression. ... Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932 ... Epitope Tag Antibodies & Reporter Protein Antibodies; Lentiviral ORF ... bio fuel heaters