Webbeffect is at locations on the DNA molecule where two thymine (T) bases occur adjacent to each other. UV irradiation causes the two T bases to covalently fuse together. Such structures are called thymine dimers and cause a distortion in the shape of DNA. Thus, when it is next time for DNA replication, a wrong base may be incorporated at the thymine WebbUV light has a short wavelength (~10 to 400 nm). UV has a lethal effect on most organisms primarily because of its ability to cause the formation of thymine dimers in DNA. Thymine dimers are two adjacent thymine bases that are abnormally linked together by covalent bonds. This dimerization inhibits DNA replication, which may lead to death of ...
13.2 Using Physical Methods to Control Microorganisms
WebbFlavonols Protect Against UV Radiation-Induced Thymine Dimer Formation in an Artificial Skin Mimic Our results suggest that flavonols can provide protection against UV radiation-induced skin damage through both antioxidant activity and direct photo-absorption. This article is open to POST-PUBLICATION REVIEW. WebbAbstract —We investigated the wavelength dependence of cyclobutane thymine dimer and (6‐4)photo‐product induction by monochromatic UV in the region extending from 150 to 365 nm, using an enzyme‐linked immunosorbent assay with two monoclonal antibodies. penarth to cardiff train
Thymine dissociation and dimer formation: A Raman and ... - PNAS
WebbAbstract —We investigated the wavelength dependence of cyclobutane thymine dimer and (6‐4)photo‐product induction by monochromatic UV in the region extending from 150 to … Webb4 aug. 2015 · Cyclobutane thymine dimers, the major photoproducts produced in UV-irradiated DNA, are the main causative agents for mutagenesis and skin cancer. This … WebbA previous study of UV-induced (254 nm) mutations in the lacI gene of Escherichia coli found that frameshift mutations accounted for about 35% of the observed mutations and that these mutations occurred predominantly at An.Tn sequences [Miller, J.H. (1985) J. Mol. Biol. 182, 48-65]. Because An.Tn sequences are hotspots for cis-syn thymine dimer … meddy grill meze and cocktail bar